A surgical instrument comprises an actuator, an extension tube and a controller, wherein the near end of the extension tube is connected with the controller, the far end of the extension tube is connected with the actuator, and the actuator can rotate relative to the far end of the extension tube. The controller comprises a bend control mechanism capable of moving in at least one direction. The extension tube comprises a first flexible component and moves in at least one direction through the bend control mechanism. The first flexible component enables the actuator to rotate relative to the far end of the extension tube towards at least one side. A bendable magazine is further provided. The actuator can bend relative to the far end of the extension tube by a larger angle through the flexible components, thereby being suitable for medical treatment under more complex clinical conditions.