#$%^&*AU2012201217A120120322.pdf#####ABSTRACT The present invention provides a novel therapeutic or preventive method, a pharmaceutical composition and use thereof, that exhibit superior anti-obesity effects (body weight5 reducing (losing) effects and/or body fat mass-reducing effects). Specifically, the present invention provides a pharmaceutical composition comprising the combination of a dipeptidyl peptidase 4 inhibitor and a sweetener having a GLP-1 secretion-stimulating action, as well as use thereof for the manufacture of a medicament. The present invention also provides a method for treating or preventing obesity, comprising administering an 10 effective amount of (a) a dipeptidyl peptidase 4 inhibitor and (b) a sweetener having a GLP- 1 secretion-stimulating action to a patient suffering from symptoms of obesity.
