The invention discloses a composition comprising at least one long chain polyunsaturated fatty acid at least one probiotic and a mixture of oligosaccharides said mixture containing at least one N acetylated oligosaccharide at least one sialylated oligosaccharide and at least one neutral oligosaccharide for use in the promotion of healthy bone growth and/or in the prevention and/or treatment of bone disease. Said bone disease is in particular osteomalacia rickets osteopenia or osteoporosis. Preferably the composition is a nutritional composition.