Steven Verhelst;Matthew S. Bogyo;Amir M. Sadaghiani
发明人:
Matthew S. Bogyo,Amir M. Sadaghiani,Steven Verhelst
申请号:
US11762735
公开号:
US08673904B2
申请日:
2007.06.13
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Provided herein are novel epoxide inhibitors of cysteine proteases, compositions comprising the epoxide inhibitors, and packaged pharmaceuticals. Also provided are methods of inhibiting a papain-family cysteine protease and methods of treating or preventing a disease by administering a composition containing an epoxide inhibitor of the invention. The compositions may be administered in combination with another therapeutic agent.