Compositions and methods related to Staphylococcal bacterium proteins

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专利权人:

University of Chicago

发明人:

Burts, Monica,Missiakas, Dominique,Schneewind, Olaf,Stranger-Jones, Yukiko

申请号：

AU2007281934

公开号：

AU2007281934B2

申请日:

2007.01.18

申请国别(地区):

AU

年份:

2012

代理人:

摘要：

The present invention concerns methods and compositions for treating or preventing a bacterial infection, particularly infection by a Staphylococcus bacteria. The invention provides methods and compositions for stimulating an immune response against the bacteria. In certain embodiments, the methods and compositions involve a secreted virulence factor, which may be EsxA and/or EsxB, and/or peptide processed by sortase, which may be SdrD, SdrE, IsdA, IsdB SdrC, Spa, IsdC, CIfA, CIfB, SasF, or combinations thereof.

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http://www.ckcest.cn/home/