ОБЩЕСТВО С ОГРАНИЧЕННОЙ ОТВЕТСТВЕННОСТЬЮ "ФАРМИНТЕРПРАЙСЕЗ" (RU)
发明人:
Небольсин Владимир Евгеньевич (RU),Кромова Татьяна Александровна (RU),Рыдловская Анастасия Владимировна (RU),Чучалин Александр Григорьевич (RU)
申请号：
RU2013150861/15
公开号：
RU2013150861A
申请日:
2013.11.14
申请国别(地区):
RU
年份:
2015
代理人:
摘要：
1. A medicament for the treatment of eosinophilic diseases, which is a compound of general formula (I): in which R and R ″ independently are hydrogen or C 1 -C 6 alkyl； R 1 is optionally substituted with 1 C 1 -alkyl, or a pharmaceutically acceptable salt thereof. The medicament according to claim 1, wherein R and R ′ are independently hydrogen or methyl, and R 3 is. The medicament according to claim 1, wherein the compound of general formula (I) or a pharmaceutically acceptable salt thereof is selected from the group consisting of the following compounds: 4. The medicine according to claim 1, wherein the eosinophilic diseases are bronchial asthma, allergic rhinitis, polyposis rhinusinosopathies, eosinophilic colitis, eosinophilic syndrome, atopic dermatitis, Cherzha-Strosa syndrome, anaphylactic shock, Quincke edema, eosinophilic eosinophilic eosinophilitis, eosinophilic eosinophilitis, eosinophilus eosinophilitis, eosinophilus eosinophilus fibrosis. 5. A pharmaceutical composition for treating eosinophilic diseases, comprising an effective amount of a compound of general formula (I): wherein R and R ″ are independently hydrogen or C 1 -C 6 alkyl； R 1 is an optionally substituted C 1 -C 1 alkyl, or a pharmaceutically acceptable salt thereof and a pharmaceutically acceptable carrier. 6. The pharmaceutical composition of claim 5, wherein R and R′ are independently hydrogen or methyl, and R is 7. The pharmaceutical composition of claim 5, wherein the compound of general formula (I) or a pharmaceutically acceptable salt thereof is selected from the group consisting of the following compounds: 8. The pharmaceutical composition of claim 5, wherein the eosinophilic diseases are bronchial asthma1. Лекарственное средство для лечения эозинофильных заболеваний, представляющее собой соединение общей формулы (I):в котором Rи R′независимо представляют собой водород или C-Cалкил；Rпредставляет собойнеобязательнозамещенный C-Cалкилом,или его фармацевтически приемлемую соль.2. Лекар
