An anti-microbial panel having an antimicrobial layer, a lightweight core layer, and a structural layer. The anti-microbial layer is preferably comprised of an anti-microbial substance such as a copper, silver, or bamboo screen, for example. The panel is configured for installing on a wall or ceiling such that one or more of said panels kills microbes in a room by microbes contacting the anti-microbial layer via air flow, for example. The panel may be made decorative by embossing or providing other decorative features.
