National University Corporation Nagoya Institute of Technology
发明人:
Kasuga, Toshihiro,Makita, Masashi
申请号:
AU2014288389
公开号:
AU2014288389A1
申请日:
2014.07.03
申请国别(地区):
AU
年份:
2015
代理人:
摘要:
Rebuilding a bone with a defect by activation of the innate self-regeneration ability of the bone requires a considerably long period of time. The purpose of the present invention is to provide a bone defect filling material that initiates a bone rebuilding action as quickly as possible following implantation and that afterward remains in the defect and continues acting to promote bone formation activity until sufficient bone formation has been achieved for the rebuilding of the defect. The present invention provides a cotton-like bone defect filling material comprising biodegradable fibers produced by electrospinning, wherein the biodegradable fibers contain 40-60 wt% of calcium phosphate particles and 10 wt% or more of silicon-eluting calcium carbonate particles, with the remainder containing 30 wt% or more of poly(L-lactic acid) resin, and the amount of the poly(L-lactic acid) resin that is non-crystalline is 75-98%.