Intra-articular injectable composition comprising: - at least one viscosupplementation agent chosen from the group: hyaluronic acid, chondroitin sulfate, queratane, queratane sulfate, heparin, cellulose and its derivatives, chitosan, xanthan, galactomannan, alginates and their respective you go out； and - a fibroblast growth medium free of any cell growth factor and free of any biological extract of animal or cellular origin, not traced and / or of undetermined composition, consisting of: Sodium chloride at a final concentration between 5000 and 8000 mg / l； L-glutamine or L-alanyl glutamine at a final concentration between 100 and 3000 mg / l； Sodium bicarbonate at a final concentration between 0 and 2000 mg / l； D-glucose at a final concentration between 2000 and 5000 mg / l； L-arginine HCl at a final concentration between 300 and 500 mg / l； Sodium acetate at a final concentration between 200 and 450 mg / l； Disodium phosphate (Na2HPO4) at a final concentration between 100 and 1500 mg / l； L-leucine at a final concentration between 50 and 200 mg / l； L-serine at a final concentration between 50 and 200 mg / l； Magnesium chloride (MgCl2, 6H2O) at a final concentration between 50 and 200 mg / l； Potassium chloride at a final concentration between 50 and 200 mg / l； L-valine at a final concentration between 20 and 150 mg / l； Sodium pyruvate at a final concentration between 10 and 75 mg / l； L-lysine HCl at a final concentration between 10 and 75 mg / l； L-histidine HCl, H2O at a final concentration between 10 and 75 mg / l； L-cysteine H2O HCl at a final concentration between 10 and 75 mg / l； Adenine (HCl) at a final concentration between 5 and 50 mg / l； L-threonine at a final concentration between 5 and 50 mg / l； Calcium chloride (CaCl2, 2H2O) at a final concentration between 0 and 22.5 mg / l； Myo-inositol at a final concentration between 5 and 50 mg / l； L-glutamic acid at a final concentration between 15 and 75 mg / l； L-asparagine H2O at a final concentratio
