Breslin, Henry Joseph,Cai, Chaozhong,He, Wei,Kavash, Robert W.
申请号:
AU2013205089
公开号:
AU2013205089A1
申请日:
2013.04.13
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
#$%^&*AU2013205089A120130516.pdf#####Abstract The present invention is directed to novel opioid receptor modulators of Formula: (I). The invention further relates to methods for preparing such compounds, pharmaceutical compositions containing them, and their use in the treatment of disorders that may be ameliorated or treated by the modulation of opioid receptors. Figure 1Figure 1 Recording distensions @ 4 min intervals 2 minutes 20 2f distension pressures- 40 4D 60 80 40 60 90 40 60 80 (mmH) intrcoonic EMGrecordings b"lcnposttned (distension time- 20 se) Zymosan treatment 0 hours 4 5 6 t t t t 1.3 nl ymsan A record treat wit record (25 m/d in 30% EtOH) oiound inieCiclnis Cnilminisinto ea 1/3