A topical composition for skin care or administration of a pharmacologicallyactive agent in form of a lotion, cream or similar comprises from 5 % to 70 %by weight of pentane-1,5-diol and a cosmetically or pharmaceuticallyacceptable carrier, with the proviso that the composition does not comprisepolysiloxane, volatile siloxane, phosphatidylcholine, creatine, carnitine,panthenol, pyruvic acid, monoglyceride of lauric acid, monoglyceride ofmyristic acid. Also disclosed are corresponding methods of administration, apatch for holding said composition against the skin, and methods forpreventing or treating a dry skin condition and of keeping skin in a humidstate.