Atrial Fibrillation Division; Inc.;St. Jude Medical
发明人:
Eric Jon Voth,D. Curtis Deno,Lev Abramovich Koyrakh,Braden Eliason
申请号:
US13839074
公开号:
US10049771B2
申请日:
2013.03.15
申请国别(地区):
US
年份:
2018
代理人:
摘要:
An embodiment of a method for solving the inverse problem of electrophysiology and determining a voltage distribution on a surface of a tissue may comprise receiving a plurality of voltages collected by a plurality of electrodes adjacent to the surface, discretizing the problem using a Finite Element Method (FEM) or a Boundary Element Method (BEM), introducing one or more regularization terms to an error minimization formulation, and solving, by a processor, the voltage distribution according to the plurality of voltages and according to the regularization terms. The regularization terms may comprise one or more of a Laplacian smoothness operator, a Tikhonov regularization matrix, a confidence matrix, and a linear operator that interpolates the plurality of electrode voltages to the tissue voltage distribution.