New phenylketone carboxylate compounds of Formula I have been discovered. These new compounds and their pharmaceutical acceptable salts have beneficial therapeutic effects to prevent or treat a condition related to (i) blood disorders, (ii) inflammation-related diseases, (iii) renal disorders and/or renal disorder complications, or (iv) a fibrosis-related organ dysfunction.已經公開式I之新苯基酮羧酸鹽類化合物。這些新化合物和它們藥學上可接受之鹽具有預防或治療與以下相關之病症的有益之治療效果:(i)血液疾患;(ii)炎症相關疾病;(iii)腎疾患和/或腎病併發症;或(iv)纖維化相關之器官功能障礙。