Old, David W.,Ngo, Vinh X.,Holoboski, Mark,Posner, Mari F.
申请号：
AU2014203599
公开号：
AU2014203599A1
申请日:
2014.07.01
申请国别(地区):
AU
年份:
2014
代理人:
摘要：
#$%^&*AU2014203599A120140717.pdf#####ABSTRACT Disclosed herein are compounds having formula (I) wherein a dashed line represents the presence or absence of a bond； Y is an organic acid functional group, or an amide or ester thereof； or Y is hydroxymethyl or an ether thereof； or Y is a tetrazolyl functional group； A is -(CH2)6-, cis -CH2CH=CH-(CH2)3-, or -CH2C=C-(CH2)3-, wherein 1 or 2 carbon atoms may be replaced by S or 0； or A is -(CH2)m-Ar-(CH2)o- wherein Ar is interarylene or heterointerarylene, the sum of m and o is 1, 2, 3, or 4, and wherein 1 -CH2- may be replaced by S or 0, and 1 -CH2-CH2- may be replaced by -CH=CH- or -C-C-； U1 and U2 are independently selected from -H, =0, -OH, -F, -Cl, and -CN； and B is aryl or heteroaryl, for use as acular hypotensive agent. H: tzm Interwoven NRPortbl DCC TZM 6467282_1.DOC - 30/6/14
