AGENTS DE DEGRADATION DE PROTEINES BCL-2 POUR LE TRAITEMENT DU CANCER

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专利权人:

BIOVENTURES; LLC

发明人:

ZHENG, GUANGRONG,ZHOU, DAOHONG,ZHANG, XUAN,KHAN, SAJID,HE, YONGHAN,ZHANG, PEIYI

申请号：

CA3088253

公开号：

CA3088253A1

申请日:

2019.01.22

申请国别(地区):

CA

年份:

2019

代理人:

摘要：

The present disclosure provides compositions and methods for selectively killing cancer cells, wherein the composition comprises a compound of Formula (I). The selective killing of cancer cells occurs with an improved potency and safety profile compared to similar compounds. In particular, the compositions and methods of the invention show reduced platelet toxicity and retained or improved toxicity in cancer cells.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/