The present invention is to offer an oxygen loath system, which supplies highly concentrated oxygen and a mist of liquid at a predetermined pressure value into a chamber, thereby enabling to efficiently cause oxygen and the mist to be absorbed into the skin and the mucous membrane of a human organism. The oxygen bath system comprises a chamber 51 of accommodating a human organism a gas supply means 11 of supplying gas containing oxygen of predetermined concentration a liquid supply means 21 of supplying a liquid a mist generating means 31 of generating a mist a pressurizing means 41 of pressurizing the mist and gas containing 25 to 40% oxygen gas generated from gas supplied from the gas supply means 11 and air, and supplying them into the chamber 51 sensors 61 of detecting measured values of air pressure, oxygen concentration, temperature and moisture within the chamber 51 and a control means 71 of controlling the environment within the chamber 51 to be within the ranges of the predetermined set values in response to the measured values detected by the sensors 61, thereby to promoting absorption of the mist and gas into the skin and mucous membrane of the human organism.