The present invention provides an extract that is extracted from cordyceps militaris for inhibiting bone erosion caused by bone metastasis. The extract may effectively reduce bone erosion due to the prostate cancer. The prostate cancer is likely to transfer to bone tissue, resulting in pathological fracture caused by serious erosion in the bone tissue of the transferred part. In addition, for the elder or amenorrhea women, bone related diseases are apt to occur because excessive activation of osteoclast reduces the amount of bone content. The extract of this invention not only alleviates the bone erosion caused by cancer cells but also inhibits the activation of osteoclast, and thus can be used as a reference for bone-related health food additives.本發明是一種萃取自北蟲草的萃取物,可用於抑制骨轉移所引起的骨侵蝕,該萃取物可以有效減少前列腺癌所引起的骨侵蝕。前列腺癌容易轉移至骨組織,造成轉移部位骨組織嚴重侵蝕而引起病理性骨折。另外,年長者或停經婦女,因破骨細胞過渡活化而使骨量減少,容易引起骨骼相關疾病。本萃取物除可減緩癌細胞所引起的骨侵蝕亦會抑制破骨細胞活性,可做為骨骼相關保健食品添加物的參考。