Systems, apparatuses, kits, and methods may provide a substance. A carrier apparatus may include a reservoir to hold a payload, a sensor to detect a target in a subject and generate data corresponding to the target, a processor to allow the payload to be accessible from the reservoir based on the data, and/or a biocompatible carrier composition to hold the reservoir, the sensor, and/or the processor. The reservoir may include a placebo reservoir, a medication reservoir, a diagnostic reservoir, and/or a modification reservoir. The payload may be made available based on a diagnosis, a detection of a target in a body, a level of the target in the body, and/or a context in which the carrier apparatus is deployed. The carrier apparatus may also include a wireless rechargeable battery to power a component of the carrier apparatus. The carrier apparatus may provide diagnostic and/or therapeutic functionality.