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METHODS AND SYSTEMS FOR DETERMINATION OF AN EFFECTIVE THERAPEUTIC REGIMEN AND DRUG DISCOVERY
专利权人:
发明人:
申请号:
EP15739850.4
公开号:
EP3099305A1
申请日:
2015.01.27
申请国别(地区):
EP
年份:
2016
代理人:
摘要:
The present invention relates to the discovery of a method for identifying a treatment regimen for a patient diagnosed with cancer, predicting patient resistance to therapeutic agents and identifying new therapeutic agents. Specifically, the present invention relates to the use of an algorithm to identify a mutation in a kinase, determine if the mutation is an activation or resistance mutation and then to suggest an appropriate therapeutic regimen. The invention also relates to the use of a pattern matching algorithm and a crystal structure library to predict the functionality of a gene mutation, predict the specificity of small molecule kinase inhibitors and for the identification of new therapeutic agents.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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