A breath analysis system that includes a handle assembly with an analysis cartridge on an upper end thereof. The handle includes a main body portion with a pressure opening and a pressure transducer therein. The analysis cartridge includes a main body portion with an upper portion that defines a breath chamber, a lower portion that defines a fluid chamber and a filter assembly that is movable between a breath capture position and an analysis position. The filter assembly has an opening defined therethrough. In the breath capture position, the opening partially defines the breath chamber and in the analysis position the opening partially defines the fluid chamber. The system also includes an analysis device with a case, a door, a controller that controls the motor and a fluorescence detection assembly and a rotation assembly positioned in the case interior. The rotation assembly includes a shroud with a funnel portion for receiving the analysis cartridge.本發明提供一種包括一手柄總成之呼吸分析系統，該手柄總成在其上端上具有一分析筒。該手柄總成在其中包括具有一壓力開口之一主體部分及一壓力傳感器。該分析筒包括：一主體部分，其具有界定一呼吸室之一上部分、界定一流體室之一下部分；及一濾光器總成，其可在一呼吸捕捉位置與一分析位置之間移動。該濾光器總成具有經界定通過其之一開口。在該呼吸捕捉位置中，該開口部分地界定該呼吸室，且在該分析位置中，該開口部分地界定該流體室。該系統亦包括一分析器件，該分析器件具有：一殼體；一門板；一控制器，其控制一馬達及一螢光偵測總成；及一旋轉總成，其定位於該殼體內部中。該旋轉總成包括具有用於接收該分析筒之一漏斗部分之一護罩。
