주식회사 바이오리더스;THE INDUSTRY AND ACADEMIC COOPERATION IN CHUNGNAM NATIONAL UNIVERSITY;BIOLEADERS CORPORATION;충남대학교산학협력단
发明人:
LEE, Il-Han,이일한,LIM, Yong Taik,임용택
申请号:
KRKR2014/004688
公开号:
WO2014/193132A1
申请日:
2014.05.27
申请国别(地区):
KR
年份:
2014
代理人:
摘要:
The present invention relates to a composition for mucus dispersion or hydration, containing a poly-γ-glutamic acid, which is a biocompatible natural polymer, and more specifically, to a composition for treating mucus hypersecretion disease, containing a poly-γ-glutamic acid or a poly-γ-glutamic acid nanogel. The present invention is useful for treating diseases associated with mucus through the effective dispersion and hydration of mucus, which is hypersecreted in vivo and has a high viscosity.La présente invention concerne une composition pour la dispersion ou l'hydratation du mucus, contenant un acide poly-γ-glutamique, qui est un polymère naturel biocompatible et, plus spécifiquement, une composition pour traiter une maladie d'hypersécrétion de mucus, contenant un acide poly-γ-glutamique ou un nanogel d'acide poly-γ-glutamique. La présente invention est utile pour traiter des maladies associées au mucus, au moyen de la dispersion et de l'hydratation efficaces du mucus, qui est hypersécrété in vivo et a une haute viscosité.본 발명은 생체친화성 천연 고분자인 폴리감마글루탐산을 함유하는 점액분산 또는 수화용 조성물에 관한 것으로, 더욱 자세하게는 폴리감마글루탐산 또는 폴리감마글루탐산 나노젤을 함유하는 점액 과분비 질환 치료용 조성물에 관한 것이다. 본 발명에 따르면, 생체에서 과다 분비되고 높은 점성을 갖는 점액질을 효율적으로 분산(dispersion) 및 수화(hydration)시킴으로서, 점액관련 질환 질병을 치료하는데 유용하다.