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Tissue targeted antigenic activation of the immune response to treat cancers
专利权人:
QU Biologics Inc.
发明人:
Gunn, Harold David
申请号:
AU2007308721
公开号:
AU2007308721B2
申请日:
2007.10.25
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
The invention provides in part methods of treating cancers of a specific organ or tissue by administering a composition that is antigenically specific for one or more microbes that are pathogenic in the specific organ or tissue in which the cancer is situated. The formulations of the invention thereby facilitate activation of a treatment response to a cancer in a particular tissue or organ. The compositions may for example include killed or attenuated microbial pathogens, and may be administered at sites distant from the cancer, for example the skin. In some embodiments, microbial species of endogenous flora that are known to cause infection in the relevant organ or tissue may be used in the formulation of the antigenic compositions. In alternative embodiments, exogenous microbial pathogens that are known to cause infection in the relevant organ or tissue may be used in the formulation of the antigenic compositions. The administration of the immunogenic compositions may be repeated relatively frequently over a relatively long period of time. In embodiments for intradermal or subcutaneous injection, dosages may be adjusted so that injections reproduce a consistent visible delayed inflammatory immune reaction at the successive site or sites of administration.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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