BALDINO, CARMEN M.,CASERTA, JUSTIN L.,LEE, CHEE-SENG,DUMAS, STEPHANE A.,FLANDERS, YVONNE L.
申请号：
CA2832865
公开号：
CA2832865A1
申请日:
2012.04.20
申请国别(地区):
CA
年份:
2012
代理人:
摘要：
Disclosed are compounds, pharmaceutical compositions containing those compounds, and uses of the compounds and compositions as modulators of casein kinase 1 (e.g., CKl?), casein kinase 2 (CK2), Pim-1, Pim-2, Pim-3, the TGFPß pathway, the Wnt pathway, the JAK/STAT pathway, and/or the mTOR pathway. Uses are also disclosed for the treatment or prevention of a range of therapeutic indications due at least in part to aberrant physiological activity of casein kinase 1 (e.g., CKl?), casein kinase 2 (CK2), Pim- 1, Pim-2, Pim-3, the TGFPß pathway, the Wnt pathway, the JAK/STAT pathway, and/or the mTOR pathway.
