Matthew Bernett,John Desjarlais,Rumana Rashid,Rajat Varma,Christine Bonzon
申请号:
US16388174
公开号:
US20190365861A1
申请日:
2019.04.18
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The present invention is directed to novel IL-15/IL-15Rα heterodimeric Fc fusion proteins and uses thereof. The IL-15/IL-15Rα heterodimeric Fc fusion proteins can be administered to a patient to treat cancer. In some cases, the IL-15/IL-15Rα heterodimeric Fc fusion protein is administered in combination with a checkpoint blockage antibody such as a PD-1 antibody.