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A METHOD FOR PREPARING A GROWTH FACTORS CONTAINING PLATELET RELEASATE
专利权人:
Power of Platelets Pte. Ltd.
发明人:
Theo GOORIS,Hossam Mostafa FAHMY
申请号:
US16462452
公开号:
US20190321408A1
申请日:
2017.11.20
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The present invention relates to a method for preparing a growth-factors containing platelet releasate from a fluid mammalian platelet concentrate, comprising the consecutive steps of subjecting the platelet concentrate to a pathogen reduction step to disrupt non-enveloped viruses; subjecting the platelet concentrate to an activation step to cause the platelets to release growth factors; recovering a fibrinogen depleted fluid platelet releasate; subjecting the fibrinogen depleted fluid platelet releasate to a second pathogen concentration reduction step to disrupt enveloped viruses; subjecting the platelet releasate to sterile filtering and recovering a filtrate liquid containing the growth factors.The platelet releasate obtained with the method of the present invention may be used as a therapeutic agent to enhance the proliferation of multi lineage cells in regenerative medicine and in the management of non healing wounds and resistant ulcers. The second indication is as a substitute to fetal bovine serum in in cell culture media.
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中国工程科技知识中心
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