Natoli, Thomas A.,Ibraghinov-Beskrovnaya, Oxana,Leonard, John P.,Yew, Nelson S.,Cheng, Seng H.
申请号:
AU2012201074
公开号:
AU2012201074A1
申请日:
2012.02.24
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
#$%^&*AU2012201074A120120322.pdf#####(57) ABSTRACT The invention relates to the treatment of polycystic kidney disease (PKD) using certain ceramide derivatives of the following formula: R I N(R2R3) HN X-R or a pharmaceutically acceptable salt thereof, wherein R -R 4, X and Y have the meanings indicated herein. These compounds may reduce the need for kidney dialysis or transplant in patients suffering from PKD.