The present invention relates to a chemodenervating agent to introduce temporal reversible infertility in a vertebrates, wherein the vertebrate may be a human, mammal, marsupial, reptile, amphibian, bird or fish, wherein the chemodenervating agent is applied either to the female or to the male reproductive tissues and/or organs In one embodiment said chemodenervating agent is the neurotoxic component of botulinum toxin free of complexing proteins.