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2 - (2,6-dichlorophenyl) - 1 - [(1s, 3R) - 3 - (hydroxy) - 5 - (3-hydroxy-3-methylbutyl) - 1-methyl-3,4-dihydroisotope-2 (1H) - 1-ethane, for the treatment of Parkinson's disease.
专利权人:
ELI LILLY AND COMPANY
发明人:
GREGORY ALAN STEPHENSON
申请号:
DO2018000103
公开号:
DOP2018000103A
申请日:
2018.04.20
申请国别(地区):
DO
年份:
2018
代理人:
摘要:
1. The invention refers to the crystal form of 2 - (2,6-dichlorophenyl) - 1 - [(1s, 3R) - 3 - (hydroxymethyl) - 5 - (3-hydroxy-3-methylbutyl) - 1-methyl-3,4-dihydroisotope-2 (1H) - IL) ethane and its pharmaceutical components. The invention also provides a method for treating cognitive failure related to Parkinson's disease or schizophrenia with crystalline form of 2 - (2,6-dichlorophenyl) - 1 - [(1s, 3R) - 3 - (hydroxymethyl) - 5 - (3-hydroxy-3-methylbutyl) - 1-methyl-3,4-dihydroisomer quinine-2 (1H) - 1) ethane.La presente invención se refiere a una forma cristalina de 2-(2,6-diclorofenil)-1-[(1S,3R)-3-(hidroximetil)-5-(3-hidroxi-3-metilbutil)-1-metil-3,4-dihidroisoquinolin-2(1H)-il]etanona, y composiciones farmacéuticas de la misma. La invención además proporciona métodos para usar una forma cristalina de 2-(2,6-diclorofenil)-1-[(1S,3R)-3-(hidroximetil)-5-(3-hidroxi-3-metilbutil)-1-metil-3,4-dihidroisoquinolin-2(1H)-il]etanona para tratar deterioro cognitivo asociado con la enfermedad de Parkinson o esquizofrenia.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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