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4-isopropyl phenyl glycitol compounds as sglt1 inhibitors
专利权人:
TAISHO PHARMACEUTICAL CO.; LTD.
发明人:
FUMIYASU SHIOZAWA,HIROYUKI KAKINUMA,KENICHI KAWABE,TAKAHIRO OI,TOMOMICHI CHONAN,YOHEI KOBASHI,YUKI IWATA
申请号:
BRPI1008653
公开号:
BRPI1008653A2
申请日:
2010.02.23
申请国别(地区):
BR
年份:
2016
代理人:
摘要:
The present invention provides 4-isopropylphenyl glucitol compounds which have no tendency to accumulate in the body and which inhibit SGLT1 activity to suppress postprandial hyperglycemia (or impaired glucose tolerance) through suppression of glucose absorption in the small intestine, whereby the compounds, for example, can suppress the onset of diabetes and metabolic syndrome or can treat these diseases. A 4-isopropylphenyl glucitol compound represented by the following formula (I) or a pharmaceutically acceptable salt thereof: wherein R1 represents a hydrogen atom, etc., R2 represents a methyl group, etc., R3 represents a C1-4 alkyl group substituted with an amino group(s), etc., and R4 represents a hydrogen atom, etc.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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