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Phenyl derivative having s1p2 antagonistic activity
专利权人:
ONO PHARMACEUTICAL CO. LTD.
发明人:
Naganawa, Atsushi,Kusumi, Kensuke,Otsuki, Kazuhiro,Sekiguchi, Tetsuya,Shinozaki, Koji,Yamamoto, Hiroshi,Yamamoto, Yasuko
申请号:
NZ71254014
公开号:
NZ712540A
申请日:
2014.03.25
申请国别(地区):
NZ
年份:
2018
代理人:
摘要:
Provided is a compound with strong human S1P2 antagonistic activity in order to develop drug products that are useful for treating S1P2 mediated disorders such as disorders that cause constriction of blood vessels, fibrosing disease, respiratory disease, and the like. The compound expressed by general formula (I) (in formula, all symbols are as described in the specification) has strong human S1P2 antagonistic activity by introducing a halogen atom or a haloalkyl group and a phenoxy group to a specific substitution site, and therefore can provide a therapeutic agent for S1P2 mediated disorders such as disorders that cause constriction of blood vessels, fibrosing disease, respiratory disease, and the like.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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