Grant A. Krafft,William L. Klein,Kirsten L. Viola,Mary P. Lambert
申请号:
US13676626
公开号:
US20130078269A1
申请日:
2012.11.14
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention provides amyloid β peptide assemblies composed of at least three amyloid β peptide subunits, wherein at least one of the amyloid β peptide subunits is an amyloid β peptide analog. The invention further relates to metal complexes of amyloid β peptide assemblies and the use of amyloid β peptide assemblies as vaccines and in the identification of agents that modulate assembly of the amyloid β peptide subunits.