Biomimetic iron-oxide-containing lipoprotein and related materials

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专利权人:

I-Wei Chen

发明人:

I-Wei Chen,Hoon Choi

申请号：

US12282308

公开号：

US08361494B2

申请日:

2007.03.06

申请国别(地区):

US

年份:

2013

代理人:

摘要：

An engineered lipoprotein including (a) a core particle or a plurality of core particles, each core particle has (i) an inner part comprising a hydrophilic active agent and a hydrophilic portion of an amphiphilic cholesterol and (ii) an outer part including a hydrophobic portion of the amphiphilic cholesterol, (b) a layer surrounding the core particle or a plurality of core particles, the layer includes a phospholipid, (c) an apoprotein associated with the layer, and optionally, (d) a homing molecule associated with at least one of the apoprotein or the phospholipid.

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