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ONSET-MITIGATING HIGH-FREQUENCY NERVE BLOCK
专利权人:
Case Western Reserve University
发明人:
Kevin L. Kilgore,Niloy Bhadra
申请号:
US14626992
公开号:
US20150165210A1
申请日:
2015.02.20
申请国别(地区):
US
年份:
2015
代理人:
摘要:
A method of blocking signal transmission through a nerve with reduced onset activity includes applying an HFAC to an axon of a nerve to block the transmission of signals through the axon. The method may also include applying a direct current (DC) to the axon, increasing the amplitude of the DC over time to a predetermined amplitude, applying the HFAC, and then decreasing the DC. The method may also include temporarily reducing the amplitude of the HFAC to permit the transmission of signals through the axon and subsequently increasing the amplitude to block transmission without triggering an onset response. The method may also include temporarily applying an unbalanced charge to the nerve and then balancing the charge over time.
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