KIM MOONSOO,LEE CHAEWOON,LEE GILNAM,YOON CHEOLHWAN,SEO JEONGBEOB,KIM JAY HAK,LEE MINWOO,JEONG HANKYUL,CHOI HYANG,JUNG MYUNG EUN,LEE KI NAM,KIM HYUN JUNG,KIM HYE KYOUNG,LEE JAE IL,KIM MISOON,CHOI SOONG
申请号：
IN201727025139
公开号：
IN201727025139A
申请日:
2017.07.14
申请国别(地区):
IN
年份:
2017
代理人:
摘要：
The disclosure provides novel chemical compounds represented by Formula (I) or a pharmaceutically acceptable salt solvate polymorph ester tautomer or prodrug thereof. The compounds can be used as an inhibitor of Trk and are useful in the treatment of pain cancer inflammation neurodegenerative disease and certain infectious diseases. In some compounds of Formula I Q is CH=CRC(O)NrR C=CC(O)NRR C= CC(0)NR4R5 or (II).
