HILL, FERGAL,MARCHAND, JEAN-BAPTISTE,DUMON, LAURENCE
申请号:
CA2631039
公开号:
CA2631039C
申请日:
2006.11.29
申请国别(地区):
CA
年份:
2015
代理人:
摘要:
The invention relates to a product which comprises a C4bp domain of a non-mammalian origin, particularly SEQ ID NO:1, SEQ ID NO:23 or SEQ ID NO:37, or avariant thereof, and an antigen. The product is desirably in the form of afusion protein. The chicken C4bp domain of SEQ ID NO:1 and SEQ ID NO:23 isalso described. Antigens include monomeric antigens such as malarial andinfluenza antigens. The C4bp domain provides for assembly of multimericcomplexes of the antigen, or mixtures thereof. The complexes are useful asvaccines.