A dose setting mechanism (1) for a resettable drug delivery device is provided comprising a dose setting member (3) and a drive member (4) for driving a piston rod in a distal direction during dose dispensing wherein the drive member (4) comprises a proximal drive member (4 ) and a distal drive member (4 ). Further a first clutch is provided for releasably coupling the proximal drive member (4 ) and the distal drive member (4 ). A spring means (7) biases the proximal drive member (4 ) and the distal drive member (4 ) in the coupled state during dose setting and dose dispensing. According to one aspect of the invention engaging means (3a 4a) are provided associated to the proximal drive member (4 ) and to the dose setting member (3) wherein the engaging means (3a 4a) are designed and arranged such that the proximal drive member (4 ) entrains the dose setting member (3) in the distal direction during dose setting but allows a relative axial movement of the proximal drive member (4 ) with respect to the dose setting member (3) in the proximal direction. Further the invention refers to an injection device with such a dose setting mechanism.
