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Neisserial bleb preparations and vaccines comprising them
专利权人:
GLAXOSMITHKLINE BIOLOGICALS S.A.
发明人:
BIEMANS, RALPH,DENOEL, PHILIPPE,FERON, CHRISTIANE,GORAJ, CARINE,POOLMAN, JAN,WEYNANTS, VINCENT
申请号:
NZ58739803
公开号:
NZ587398A
申请日:
2003.07.31
申请国别(地区):
NZ
年份:
2012
代理人:
摘要:
A Neisserial bleb preparation from a neisserial strain which has had the expression of FrpB downregulated or deleted. The Neisserial bleb preparation can further be derived from a strain in which selected outer membrane proteins, capsular polysaccharide genes and lipid A genes are downregulated or deleted and selected outer membrane protein antigens are upregulated.
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