Antimicrobial preparation comprising from 0.003 to 1% by weight based on the preparation of octenidine dihydrochloride encapsulated in liposomes, comprising from 0.5 to 20% by weight of phosphatidylcholine based on the complete preparation.Preparado antimicrobiano que comprende de 0,003 a 1% en peso en base al preparado de dihidrocloruro de octenidina encapsulado en liposomas, que comprende de 0,5 a 20% en peso de fosfatidilcolina en base al preparado completo.