The present invention provides a pharmaceutical composition comprising a mushroom, a rhizome, a fruit, a leaf, a flower, algae, an energy-rich liquid, a salt-rich liquid, an assist agent and an anti-oxide agent. Said pharmaceutical composition has ability to improve autoimmunity, protect from the side-effects caused by chemical cancer drugs and increase the functions of chemical pancreatic cancer drugs.本發明提供一種用於降低胰臟癌治療藥物副作用之醫藥組合物,包括一菇類、一根莖類、一果實種子類、一葉類、一花類、一藻類、一能量配置液、一鹽類配置液、一補助劑以及一抗氧化劑。所述醫藥組合物具有提升自體免疫力、免於一癌症治療藥物所造成的副作用或提升該化學治療癌症藥物治療癌症之功效。