Combination therapy for treating hearing and balance disorders

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专利权人:

发明人:

Svetlana Adamsky,Elena Feinstein

申请号：

US14588955

公开号：

US09434946B2

申请日:

2015.01.04

申请国别(地区):

US

年份:

2016

代理人:

摘要：

The present application relates to combinations of inhibitors directed at down-regulation of genes associated with hearing loss including HES1, HES5, HEY2, CDKN1B and NOTCH1, exhibiting a beneficial effect and useful in treating or attenuating hearing loss, treating balance impairment, promoting the replacement, regeneration, or protection of otic (sensory) hair cells of the inner ear, and or effecting hearing restoration/regeneration.

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