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Peptide particle formulation
专利权人:
Reid M. Rubsamen
发明人:
Reid M. Rubsamen,David Earl Heckerman
申请号:
US13153826
公开号:
US09408906B2
申请日:
2011.06.06
申请国别(地区):
US
年份:
2016
代理人:
摘要:
A composition as disclosed is comprised of a plurality of groups of particles. The particles are comprised of a biocompatible polymer which maybe a co-polymer such as PLGA combined with a peptide of a sequence of interest, e.g. a sequence which corresponds to a sequence presented on a surface of a cell infected with a virus. A plurality of different groups of particles are provided in the formulation wherein the particles within any single group include peptides of identical amino acid sequence. The particles are sized such that they are sufficiently large so as to prevent more than the contents of a single particle from being presented to a single immune system cell.
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