Gary A. Nichols,Robert E. Halvachs,Gary L. Cantrell,Kevin R. Roesch,Joseph P. Haar, Jr.
申请号:
US12668218
公开号:
US08383649B2
申请日:
2008.06.25
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention relates to novel crystalline forms of naltrexone methobromide including hydrated and solvated forms. The invention also describes methods of preparing the various crystalline forms. The present invention also relates to pharmaceutical compositions containing crystalline forms of naltrexone methobromide, as well as methods of treating or preventing opioid induced side effects by administering the pharmaceutical compositions.