This application relates to benzyl - 1H pyrazolo [3,4-b] pyridines of formula (i), wherein R1 represents Hydrogen or Fluorine, and R2 represents Hydrogen or Fluorine, R3 represents Hydrogen or Fluorine, Chlorine, R4 represents Hydrogen or Methyl, Chlorine, Fluorine, with the condition that the least two The Radicals R1, R2, R3 and R4 are different from Hydrogen, R5 represents Hydrogen or Fluorine,R6 represents Methyl, R7 R6 and R7 represents Methyl, or together with the carbon Atom to which they bind and form a Ring ciclopropilo, oxides, salts, solvates of oxides, Salts and solvates of oxides or salts thereof.Is the preferred compound: 2 - [1 - (2,3 - difluorobencil) - 5 - fluoro - 6 - methyl - 1 H - pyrazolo [3,4-b] pyridin-3-yl] - dimethyl - 5 - 7, 7, 7 - dihydro - 5h pyrrolo [2,3-e] [1,2,4] triazin - 6 - One among others. These compounds are useful for the treatment of cardiovascular diseases.La presente solicitud se relaciona con bencil-1 H-pirazolo[3,4-b]piridinas de formula (I), en la que R1 representa hidrogeno o fluor, R2 representa hidrogeno o fluor, R3 representa hidrogeno, cloro o fluor, R4 representa hidrogeno, cloro, fluor o metilo, con la condicion de que por lo menos dos de los radicales R1, R2, R3 o R4 son diferentes de hidrogeno, R5 representa hidrogeno o fluor, R6 representa metilo, R7 representa metilo, o R6 y R7 junto con el atomo de carbono al que se unen forman un anillo ciclopropilo, y los oxidos N, sales, solvatos, sales de los oxidos N y solvatos de los oxidos N o sales de los mismos. Es compuesto preferido: 3-[1-(2,3-difluorobencil)-5-fluoro-6-metil- 1 H-pirazolo[3,4-b]piridin-3-il]-7, 7 -dimetil-5, 7 -dihidro-6H-pirrolo[2,3-e][1,2,4]triazin-6-ona entre otros. Dichos compuestos son utiles para el tratamiento de enfermedades cardiovasculares.
