Methods of treating cancer

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专利权人:

Inc.;Tesaro

发明人:

FENG, Bin,RAMASWAMY, Sridhar,WANG, Jing Yu,XIAO, Yonghong,ZHOU, Yinghui

申请号：

AU2018394976

公开号：

AU2018394976A1

申请日:

2018.12.27

申请国别(地区):

AU

年份:

2020

代理人:

摘要：

The present invention provides methods of treatment of cancer patients having deficiency in at least one non-BRCAl/2 gene involved in the homologous recombination repair (HRR) pathway with a poly(ADP-ribose) polymerase (PARP) inhibitor such as niraparib. In particular, cancer patients having a deficiency in at least one gene selected from the group consisting of BRCAl, BRCA2, ATM, ATR, BAPl, BARDl, BLM, BRIPl, MREl l A, NBN, PALB2, RAD51, RAD51B, RAD51C, RAD51D, RAD52, RAD54L, XRCC2, TP53, or RBI can benefit from treatment with niraparib.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/