East Tennessee State University Research Foundation
发明人:
Theodoor Hagg,Yue Zou
申请号:
US16677945
公开号:
US20200147077A1
申请日:
2019.11.08
申请国别(地区):
US
年份:
2020
代理人:
摘要:
A method of treating a subject suffering from an ischemic disease associated with Ca2+ overload is provided, the method including administering to the subject an effective amount of an inhibitor of ataxia telangiectasia and Rad3-related (ATR) kinase. Also provided is a method of treating a subject suffering from acute ischemic stroke, the method including administering to the subject an effective amount of the ATR kinase inhibitor berzosertib.