ANTICORPS BIFONCTIONNEL ANTI-CTLA4 ET ANTI-PD -1, COMPOSITION PHARMACEUTIQUE ET UTILISATION ASSOCIÉES

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专利权人:

Inc.;Akeso Pharmaceuticals

发明人:

申请号：

EP17842896.7

公开号：

EP3511346A1

申请日:

2017.08.22

申请国别(地区):

EP

年份:

2019

代理人:

摘要：

An anti-CTLA4(cytotoxic T lymphocyte associated antigen4)and anti-PD-1(programmed cell death 1)bifunctional antibody.a pharmaceutical composition thereof and use thereof.Particularly,the anti-CLTA4 and anti-PD-1 bifunctional antibody comprises afirst protein functional domain that targets PD-1 and a second protein functional domain that targets CTLA-4. The bifunctional antibody can bind to CTLA-4 and PD-1 specifically, relieve immunosuppression of CTLA4 and PD-1 on an organism specifically, activate T lymphocytes,and thus has good application prospects.

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/