METHODES THERAPEUTIQUES VASCULAIRES ET COMPOSITIONS IMPLIQUANT LA REDUCTION OU LA PREVENTION DE PROCESSUS ASSISTES C-JUN

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专利权人:

UNISEARCH LIMITED

发明人:

KHACHIGIAN, LEVON MICHAEL

申请号：

CA2477283

公开号：

CA2477283C

申请日:

2003.02.27

申请国别(地区):

CA

年份:

2013

代理人:

摘要：

The present invention provides a method of preventing or reducing restenosis,neointima formation, graft failure, atherosclerosis, angiogenesis and/or solidtumour growth in a subject. The method comprises administering to the subjecta prophylactically effective dose of a nucleic acid which decreases the levelof c-Jun mRNA, c-Jun mRNA translation or nuclear accumulation or activity of c-Jun. It is preferred that the nucleic acid is a DNAzyme that targets c-JunmRNA.

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中国工程科技知识中心

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http://www.ckcest.cn/home/