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INTRACELLULAR OSTEOPONTIN REGULATES THE LINEAGE COMMITMENT OF LYMPHOID SUBSETS
专利权人:
发明人:
Harvey Cantor,Jianmei Wu Leavenworth
申请号:
US15506868
公开号:
US20170269076A1
申请日:
2015.08.27
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Methods for diagnosing and prognosing autoimmune diseases and T cell lymphomas are provided, for example by measuring levels of intracellular osteopontin (OPN-i). Also provided are screening methods for identifying activators and inhibitors of the transcription factor Bcl6, which is involved in T cell activation/differentiation. Other aspects of the disclosure provide methods for enhancing adoptive T cell transfer.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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