The United States of America; as represented by the Secretary; Department of Health & Human Servic
发明人:
Bira Arya,Purevdorj Olkhanud,Juan Espinoza
申请号:
US15204789
公开号:
US20160310609A1
申请日:
2016.07.07
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention features compositions and methods that make use of complexes comprising one or more inhibitory nucleic acids and a targeting polypeptide, wherein the targeting polypeptide consists of a cell surface receptor ligand. The compositions can be used in methods of silencing gene expression in a cell, delivering agents to a target cell, and in treating or preventing a disease or disorder in a subject.