[Problem]To provide a guide tube equipped with a balloon for puncture, devised to ensure a deeper level of puncture when the balloon is punctured with a puncture needle, in order to safely and reliably ensure a route for percutaneous approach to the inside of the body[Solving Means]A guide tube equipped with a balloon for puncture, includes a main body tube 1 equipped with a balloon 2 on its tip end-side surface, the tube 1 having a main lumen 5 for insertion of an endoscope, which penetrates from the rear end to the tip end, and a sub lumen 6 brought in gas/liquid communication with the inside of the balloon 2, the main lumen 5 being provided, at its rear end, with an endoscope insertion part, and the sub lumen 6 being provided, at its rear end, with connectors 3 for inflating and contracting operations of the balloon 2, wherein the balloon on the tip end-side surface is used as an outer balloon 21, a needle through hole, through which a puncture needle 22 sufficiently passes, is formed in a wall surface of the main body tube 1 located inside the outer balloon 2, the hole is blocked air-tightly with an inflatable sheet material, and the sheet material is provided as an inner balloon, the inner balloon being so formed that, upon inflation of the outer balloon 2, the inner balloon 9 inflates and projects from the needle through hole toward the inside of the main lumen 5 due to the internal pressure of the outer balloon 2, so that the tip end of the puncture needle 22 can be pierced into the inflating and projecting part.